Thioguanine: 40 mg Tablets

Thioguanine ANTINEOPLASTIC Highlights of Prescribing Information Oral purine analog antineoplastic that may be useful as adjunctive treatment for acute lymphocytic or granulocytic leukemia in dogs or cats Contraindications: Hypersensitivity to thioguanine Caution: Hepatic dysfunction, bone marrow depression, infection, renal function impairment (adjust dosage), or history of urate urinary stones Potentially mutagenic & teratogenic; use milk… Read More »

Thiotepa Lyophilized Powder for Injection: 15 mg & 30 mg in vials

Thiotepa ANTINEOPLASTIC Highlights of Prescribing Information Antineoplastic used systemically for carcinomas, intracavitary for neoplastic effusions, & intravesical for transitional carcinomas; rarely used in small animal oncology Contraindications: Hypersensitivity to thiotepa; Caution: Hepatic dysfunction, bone marrow depression, infection, tumor cell infiltration of bone marrow, renal dysfunction, or history of urate urinary stones Adverse Effects: Leukopenia most… Read More »

Thiola (Tiopronin): 100 mg Tablets

Tiopronin (Thiola) 2-MPG ANTIUROLITHIC (CYSTINE) AGENT Highlights of Prescribing Information Drug for prevention (& treatment) of cystine urolithiasis Cautions: Agranulocytosis, aplastic anemia, thrombocytopenia or other significant hematologic abnormality, impaired renal or hepatic function, or sensitivity to either tiopronin or penicillamine Adverse Effects: Coombs’-positive regenerative sphero-cyte anemia, aggressiveness, proteinuria, thrombocytopenia, elevations in liver enzymes, dermatologic effects,… Read More »

Tonocard (Tocainide HCL): 400 mg, 600 mg Tablets

Tocainide HCL (Tonocard) ORAL ANTIARRHYTHMIC Highlights of Prescribing Information Oral antiarrhythmic with similar activity as lidocaine; not commonly used in veterinary medicine Contraindications: Hypersensitivity reactions to it or amide-type local anesthetics, 2nd or 3rd degree AV block & not being artificially paced. Caution: Heart failure, hematologic abnormalities, or preexisting bone marrow failure. Adverse Effects: CNS… Read More »

Demadex (Torsemide): 5 mg, 10 mg, 20 mg, & 100 mg Tablets

TORSEMIDE (Demadex, Torasemide) LOOP DIURETIC Highlights of Prescribing Information Potent loop diuretic potentially useful for adjunctive treatment of CHF in dogs & cats; very little information available on clinical use in veterinary medicine Approximately 10X more potent, longer diuretic action, & more potassium-sparing (in dogs) than furosemide May be more expensive than furosemide, but tablets… Read More »

Dental Disease and Care

An oral examination should be performed each time a puppy or kitten is presented. Many pathologic or potentially pathologic conditions can be detected at an early age and corrective measures taken. Introducing the pet owner to the concept of oral home care and regular professional dental prophylaxis are the two most important responsibilities of the… Read More »

The Pancreas

Inflammatory Pancreatic Disease The pancreas is a unique organ possessing both exocrine (digestive) and endocrine (hormonal) functions. Inflammatory pancreatic disease affecting only the exocrine portion is extremely uncommon in young dogs and cats (). Consequently, inflammatory pancreatic disease, that is, acute pancreatitis or relapsing pancreatitis that more commonly affects older dogs and cats, has been… Read More »

Autoimmune Disorders

Pemphigus complex the pemphigus complex comprises a group of rare autoimmune diseases described in dogs and cats the diseases are vesiculobullous ulcerative disorders of the skin and often the mucous membranes autoantibody is directed against the epidermal intercellular cement substance and may be demonstrated by direct immunofluorescence testing histologically the pemphigus complex is characterized by… Read More »

Dyrenium (Triamterene): 50 mg, 100 mg Capsules

TRIAMTERENE (Dyrenium) POTASSIUM-SPARING DIURETIC Highlights of Prescribing Information Potassium-sparing diuretic that may be considered as an alternative to spironolactone for treating CHF in dogs; limited clinical experience with this drug in dogs/cats Contraindications: Anuria, severe or progressive renal disease, severe hepatic disease, hypersensitivity to triamterene, preexisting hyperkalemia, concurrent therapy with another potassium-sparing agent (spironolactone, amiloride)… Read More »